Born in Thailand to Cambodian parents Pisay came to Seattle at the age of two. As a way of holding onto her heritage, her parents encouraged Pisay to sing and dance in Cambodian as often as there were guests in the house. However as she got older and started acting in school plays, she was discouraged from pursuing a career in the arts in place of something more academic. Pisay obliged her parents by attending the University of Washington but quickly left after only a year to obtain a fashion design degree from Seattle Central Community College.
She was immediately hired by Tommy Bahama and then onto Unionbay but found that even the fashion industry couldn't give her the full creative freedom she desired. After just two years Pisay left her full time job to travel and try her hand at being a wardrobe stylist. It was during this period that she met a model who often complained about having to memorize lines for auditions.
Pisay began giving the model pointers and tips for her reading. The model was so impressed by her advice she pushed Pisay onto her agent. After booking a regional Qwest commercial on her very first audition the Agency agreed to represent Pisay despite the fact that she had no other formal training. Since then Pisay has appeared in many other local and regional commercials as well as radio ads. Her role as Inona in THE WHOLE TRUTH is her first big movie break.